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Since the newer agents are generally continuously in a therapeutic range, they have been shown to be more effective than coumadin at reducing the risk of stroke.

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exenatide byetta ; probenecid benemid ; some nonsteroidal anti-inflammatory drugs nsaids ; aspirin or other salicylates including pepto-bismol ; a blood thinner such as warfarin coumadin, jantoven ; sulfa drugs bactrim, gantanol, gantrisin, septra, smx-tmp, and others ; a monoamine oxidase inhibitor maoi ; and other oral diabetes medications, especially acarbose precose , metformin glucophage , miglitol glyset , pioglitazone actos , or rosiglitazone avandia .

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cyclosporine; lithium; methotrexate; probenecid; a blood thinner warfarin, coumadin, jantoven ; heart or blood pressure medication, including a diuretic or water pill ; or steroid medicine such as prednisone .

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drugs known to interact with celebrex include blood pressure medications called angiotensin-converting enzyme ace inhibitors, like benazepril lotensin , captopril capoten , and enalapril vasotec , as well as angiotensin ii receptor antagonists such as candesartan atacand , eprosartan teveten , and irbesartan avapro aspirin drugs used to treat rheumatoid arthritis and other conditions, including methotrexate trexall, rheumatrex the anti-fungal drug fluconazole diflucan the bipolar drug lithium eskalith, lithobid diuretics water pills other nsaids, including over-the-counter nsaids motrin, advil and other pain relievers like naproxen aleve blood thinners, such as warfarin coumadin .

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pradaza and eliquis require twice a day dosing, unlike xarelto and savaysa and coumadin which only have to be taken once a day.

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